Season: 2025
| # | Team | MP | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  St. Louis City II | 28 | 17 | 6 | 5 | 60 | 37 | 23 | 62 |
| 2 |  The Town | 28 | 14 | 6 | 8 | 59 | 36 | 23 | 52 |
| 3 |  Colorado Rapids II | 28 | 15 | 5 | 8 | 55 | 40 | 15 | 51 |
| 4 |  Real Monarchs | 28 | 13 | 8 | 7 | 55 | 42 | 13 | 51 |
| 5 |  Minnesota United II | 28 | 12 | 6 | 10 | 45 | 42 | 3 | 44 |
| 6 |  North Texas | 28 | 11 | 6 | 11 | 46 | 55 | -9 | 43 |
| 7 |  Vancouver Whitecaps II | 28 | 11 | 5 | 12 | 61 | 54 | 7 | 42 |
| 8 |  Ventura County | 28 | 11 | 6 | 11 | 48 | 51 | -3 | 41 |
| 9 |  Austin II | 28 | 10 | 8 | 10 | 35 | 36 | -1 | 41 |
| 10 |  Portland Timbers II | 28 | 10 | 6 | 12 | 47 | 54 | -7 | 38 |
| 11 |  Houston Dynamo FC II | 28 | 9 | 6 | 13 | 40 | 47 | -7 | 37 |
| 12 |  Tacoma Defiance | 28 | 10 | 4 | 14 | 62 | 67 | -5 | 36 |
| 13 |  Los Angeles FC II | 28 | 9 | 4 | 15 | 47 | 61 | -14 | 33 |
| 14 |  Sporting KC II | 28 | 3 | 6 | 19 | 30 | 67 | -37 | 17 |